A system of wireless access monitoring and control for a smart home is presented in this paper. The transmit interface of this system include ZigBee-ZigBee modules, ZigBee modules-PC and PC-PDA. Where PDA plays a portable indoor remote controller with intelligent, we can monitor the information of indoor environment and control in real time if necessary. In order to obtain a reasonable solution between thermal comfort and saving energy in smart home, a CMAC based PMV evaluate scheme is proposed and implemented in this paper. Besides, the lighting control also is determined by ZigBee based wireless sensor to obtain a well illumination space. Experiment results shown that the proposed system based on ZigBee transmit and CMAC PMV thermal comfort scheme is feasible to implement in real time application for smart home.