This paper proposes wireless network physiological signal monitoring system which integrates a System on a Chip (SoC) platform and Bluetooth wireless network technologies in homecare technology. The system is constituted of three parts including mobile sensing unit, Bluetooth module and web-site monitor unit. Firstly, we use acquisition sensors for physiological signals, an MCU as the front-end processing device, and several filter and amplifier circuits to process and convert signals of electrocardiogram (ECG), body temperature and heart rate into digital data. Secondly, a Bluetooth module was used to transmit digital data to the SoC platform in wireless manner. Finally, we utilized an SoC platform, as a Web server additionally, to detect the body temperature and the heart rate. Our proposed SoC platform demonstrated that the acquired physiological signals could be displayed on a Web page or collected into a nursing center in real-time through RJ-45. Our results show the SoC wireless network for physiological signal monitoring is feasible for future applications in homecare technology. (17 refs)