This study intended to investigate the effect of integrating RFID information systems into cancer chemotherapy infusion dispensing procedures on the efficiency of patient care. After the ad hoc committee selected the improvement program based on grey multi-attribute decision-making, improvements were made to the information system and infusion dispensing procedures, and relevant professionals fully communicated with one another to apply the RFID information system to the improvement program. After the RFID information system was integrated with the infusion dispensing procedures, the average total operating time for dispensing chemotherapy infusions was reduced from 24.55 minutes to 12.2 minutes, which was a decrease of 50.3%. The objective of requiring less time than the standard (16 minutes) was achieved, verifying that the integration of better RFID information system programs indeed can reduce the time required for providing patients with service. The improvement program can both increase operating efficiency and patient safety, and can be provided as a reference to relevant industries.