In recent years, the robot development has been fast expanding to many areas such as entertainment, home task, security, medical care, etc. Accordingly, this paper proposes a simple but reliable robot communication interface and local-loop control system based on RS232 and 8051 microprocessor, suitable use for various kinds of robot control. In this proposed scheme, the robot action commands stored in the database using C++ Builder can be transmitted from the Command-Transmission Microprocessor (CTM) and then received by the individual authorized Action-Processing Microprocessor (APM) via RS232. Real-time implementation results are presented to demonstrate the effectiveness of the proposed approach in term of robust, simple, flexible and efficient performance.